AVISE Lupus

The Advanced Lupus Test

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AVISE® Lupus is a 10-marker diagnostic test containing Cell-Bound Complement Activation Products (CB-CAPs) and SLE associated markers designed to aid healthcare providers in a timely differential diagnosis of SLE.

What is included in AVISE Lupus?

BiomarkersAVISE LupusAVISE CTD
10-marker Lupus diagnostic test containing Cell-Bound Complement Activation Products (CB-CAPs)
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AVISE Index Calculation Value
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Extractable Nuclear Antigen (ENA) Panel 
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Rheumatoid Arthritis Panel 
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Antiphospholipid Syndrome – APS panel 
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Thyroid panel 
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AVISE Lupus contains the following biomarkers:

AVISE® Lupus contains patented Lupus (SLE) biomarkers, CB-CAPs, which help to offer a 22% greater sensitivity than C3/C4, and 48% greater sensitivity than anti-dsDNA.

Clinical Utility:

The AVISE Lupus test is an ideal test for ANA positive patients with a clinical suspicion of lupus.

Testing method:

The AVISE Lupus test is composed of a two-tier testing method:

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AVISE Lupus Test Report:

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References:

  1. Cell-bound complement activation products in SLE. Ramsey-Goldman R, et al. Lupus Science and Medicine. 2017.
  2. Cell-bound complement activation products in systemic lupus erythematosus: comparison with anti-double-stranded DNA and standard complement measurements. Putterman C. et al. Lupus Science and Medicine. 2014.
  3. Systemic lupus erythematosus and primary fibromyalgia can be distinguished by testing for cell-bound complement activation products. Wallace D. et al. Lupus Science & Medicine. 2016.
  4. The AVISE Lupus Test and Cell-bound Complement Activation Products Aid the Diagnosis of Systemic Lupus Erythematosus. Mossell J. et al. The Open Rheumatology Journal. 2016.
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To learn more about AVISE testing please click the link below.

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