Publications

 

Merrill J, et al. LSM 2018 – Erythrocyte-bound C4d in combination with complement and autoantibody status for the monitoring of SLE.

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Ramsey-Goldman R, et al. LSM 2017 • Cell-bound complement activation products in SLE

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Buyon J, et al. LSM 2016 – Reduction in EC4d and anti-C1q antibodies associate with clinical improvement in SLE.

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Putterman C, et al. LSM. 2014. Cell_bound complement activation products in systemic lupus erythematosus.

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Wallace D, et al. LSM. 2016. Systemic lupus erythematosus and primary fibromyalgia can be distinguished by testing for cell-bound complement activation products.

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AVISE Lupus is indicated for the diagnosis of suspected SLE patients. AVISE CTD is indicated for differential diagnosis of autoimmune connective tissue diseases.

Clinical Validity



Putterman, C., et al. (2014). Cell bound complement activation products in systemic lupus erythematosus. Lupus Science & Medicine.

Clinical Utility




Health Economic Outcome Research

Analytical Validity

SLE Review Articles


Case Study

Medical Society Guidelines

Publications related to AVISE SLE Monitor

AVISE SLE Monitor is indicated for the ongoing assessment of SLE disease activity

Clinical Validity






Orbai, A.M., et al. (2015). Anti-C1q antibodies in systemic lupus erythematosus. Lupus.




Clinical Validity




Analytical Validity

CB-CAPs Review Articles

Ramsey-Goldman, R., et al. (2017). Cell-bound complement activation products in SLE. Lupus Science and Medicine.


Ahearn, J., et al. (2017). Cell-bond complement activation products as lupus biomarkers: diagnosis, monitoring and stratification. Expert Review of Clinical Rheumatology.

PC4d is indicated for diagnosed SLE patients as a marker associated with thrombosis.

Clinical Validity



Avise MTX is indicated for RA patients receiving Methotrexate therapy as an objective measure of therapeutic exposure.

Clinical Validity



Dervieux, T., et al. (2013). Methotrexate polyglutamation in relation to infliximab pharmacokinetics in rheumatoid arthritis. Annals of the Rheumatic Diseases. 




Analytical Validity

Review Articles


Kremer J. et al. (2004). Toward a Better Understanding of Methotrexate. Arthritis & Rheumatology.

AVISE HCQ is indicated for SLE patients receiving Hydroxychloroquine therapy as an objective measure of drug exposure.

Clinical Validity

Petri, M., et al. (2020). Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy. Arthritis & Rheumatology.



Costedoat-Chalumeau, N., et al. (2013). Hydroxychloroquine in systemic lupus erythematosus: results of a French multicentre controlled trial (PLUS Study). Annals of the Rheumatic Diseases.

Analytical Validity

AVISE HCQ Review Articles


Methotrexate polyglutamates (MTXPGs)

Anti-Carbamylated Protein Antibodies (Anti-CarP)

Weinstein, A., et al. (2019). Reevaluating Serologic Markers of Poor Prognostic Factors in Rheumatoid Arthritis. The Journal of Rheumatology.


Selected Abstracts

Petri, et al. 2020. Role of Platelet C4d in Thrombosis and Lupus Nephritis. Arthritis Rheumatol.